Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BMP15 All Species: 6.06
Human Site: S261 Identified Species: 13.33
UniProt: O95972 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95972 NP_005439.2 392 45055 S261 E E F M E R E S L L R R T R Q
Chimpanzee Pan troglodytes XP_529247 393 45083 L262 E F M E R E S L L L R R T R Q
Rhesus Macaque Macaca mulatta XP_001083980 393 45455 F262 E F M E R E S F L L R R T R Q
Dog Lupus familis XP_549005 393 44984 S262 G F I E K D S S L L R R A R Q
Cat Felis silvestris
Mouse Mus musculus Q9Z0L4 392 44879 F261 L T D R E S S F L M R S V R Q
Rat Rattus norvegicus Q6HA10 452 50994 S321 S G A P D A G S W L P S P G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510645 359 41050 Y231 F N D T H Q G Y Q E V G P P L
Chicken Gallus gallus Q90752 405 46039 R270 G G D W A Q L R P L L V T F G
Frog Xenopus laevis P30885 401 45970 T271 Q M R P L L I T F S H D G R G
Zebra Danio Brachydanio rerio A8E7N9 412 47049 R281 L D S I G K E R R S H S K T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48970 395 43818 S264 S S E Y R Q C S K R N R R N K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 93.8 74 N.A. 63.5 23.8 N.A. 41.5 26.1 25.6 25 N.A. N.A. N.A. N.A. 26
Protein Similarity: 100 98.4 95.6 84.2 N.A. 75.7 38.9 N.A. 56.6 42.9 42.8 44.1 N.A. N.A. N.A. N.A. 43.8
P-Site Identity: 100 53.3 53.3 46.6 N.A. 33.3 13.3 N.A. 0 13.3 6.6 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 53.3 53.3 53.3 N.A. 40 26.6 N.A. 6.6 20 20 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 10 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 28 0 10 10 0 0 0 0 0 10 0 0 0 % D
% Glu: 28 10 10 28 19 19 19 0 0 10 0 0 0 0 0 % E
% Phe: 10 28 10 0 0 0 0 19 10 0 0 0 0 10 0 % F
% Gly: 19 19 0 0 10 0 19 0 0 0 0 10 10 10 19 % G
% His: 0 0 0 0 10 0 0 0 0 0 19 0 0 0 0 % H
% Ile: 0 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 10 0 0 10 0 0 0 10 0 10 % K
% Leu: 19 0 0 0 10 10 10 10 46 55 10 0 0 0 10 % L
% Met: 0 10 19 10 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 10 0 0 10 0 % N
% Pro: 0 0 0 19 0 0 0 0 10 0 10 0 19 10 0 % P
% Gln: 10 0 0 0 0 28 0 0 10 0 0 0 0 0 46 % Q
% Arg: 0 0 10 10 28 10 0 19 10 10 46 46 10 55 19 % R
% Ser: 19 10 10 0 0 10 37 37 0 19 0 28 0 0 0 % S
% Thr: 0 10 0 10 0 0 0 10 0 0 0 0 37 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 10 10 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _